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Ethics and research in psychiatry: Consent, capacity, and bioethics
April 1, 2020
Bioethics
Book Chapter
This chapter provides an overview of the principles underlying ethical procedures in psychiatric research, with a specific focus on populations with mental disorders and research
The relationship between independent and dependent life events and depression symptoms in Sri Lanka: a twin and singleton study
February 1, 2020
Twin Research
Journal Article
Life events have been associated with a variety of mental health conditions including depression. There is a scarcity of research in South Asia exploring the
Ethics, a critical friend of research
January 16, 2020
Bioethics
Journal Article
Ethics is perceived by some at least, as an opponent of research, or as a barrier or even a hindrance. Ethicists and researchers seem to
Determination of testicular estrogen receptor alpha expression of male chickens (Gallus domesticus) with age
June 1, 2019
Genetics
Journal Article
Estrogen activity, a central component of reproductive growth, is regulated by the receptor proteins, estrogen receptor alpha (ERα), and ER beta (ERβ) in chickens as
The association between emotional eating and depressive symptoms: a population-based twin study in Sri Lanka
May 1, 2019
Twin Research
Journal Article
This study investigated the genetic and environmental contributions to emotional overeating (EOE) and depressive symptoms, and their covariation, in a Sri-Lankan population, using genetic model-fitting
Effect of exogenous estrogen treatment on gonadal morphology, morphometry and estrogen receptor alpha mRNA expression in gonads of male chickens (Gallus domesticus)
March 1, 2019
Genetics
Journal Article
The current study was designed to investigate the post-hatching ERα expression in left gonads of male chickens along with gonadal morphology when the exogenous estradiol
Agreement between subjective and objective measures of sleep duration in a low-middle income country setting
December 1, 2018
Twin Research
Journal Article
Describe sleep duration in adult Sri Lankans and determine the bias and agreement of self-report and actigraphic assessments.
Literature Review for Identifying the Research Gaps on Taxonomy, Molecular Systematics and Conservation Status of Endemic Skink Genus Lankascincus (Squamata: Scincidae)
November 29, 2018
Genetics
Abstract
Sri Lanka harbours a rich endemism for skinks. As a key link in the food-chain, skinks support to balance the ecosystem and help retaining eco-cycles,
Effect of exogenous estradiol on the gonadal morphology and morphometry of the male chickens (Gallus domesticus)
September 27, 2018
Genetics
Abstract
Initial validation of zygosity determination questionnaire for Sri Lankan twins using STR analysis of 15 unlinked loci and the gender-determining marker amelogenin
August 27, 2018
Genetics
Abstract
Zygosity determination is an essential component in behavioural genetics which uses twins for research. Although genetic markers are considered gold-standard, questionnaire based methods are preferred in
Determination of testicular estrogen receptor α expression of male chickens (Gallus Domesticus) with age
August 24, 2018
Genetics
Abstract
Estrogen activity within living cells is regulated by its receptor, estrogen receptor α (ER α) and estrogen receptor β (ER β) in chickens as in
Agricultural, Economical and Ecological Importance of Phoenix pusilla (Ceylon Date Palm) and Its Future Research Perspectives
February 1, 2018
Genetics
Abstract
Phoenix pusilla, is an underutilised fruit crop, and an untouched genetic resource, facing a severe genetic loss due to the negligence of the public and
Protein Overexpression in Different E. coli Strains for Industrial Scale Drug Development in Sri Lanka
February 1, 2018
Genetics
Abstract
Research and industrial scale protein overexpression for pharmaceutical products uses Escherichia coli (E. coli) strains due to their well-characterised genome and easy manipulation. This review
Comparison of DNA isolation and dominant and co-dominant molecular markers to reveal the genetic sex of Gallus domesticus (Domestic chickens)
February 1, 2018
Genetics
Abstract
The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka
January 1, 2018
Twin Research
Journal Article
The disease burden related to mental disorders and metabolic syndrome is growing in low-and middle-income countries (LMIC). The Colombo Twin and Singleton Study (COTASS) is
Sri Lankan Twin Registry Biobank: A Resource for Human Genetic Research in Sri Lanka
December 4, 2017
Genetics
Abstract
Bio banking is an innovave concept of storing and sharing biological samples for current and future research. Even though it is well established in the
Polymerase Chain Reaction (PCR) Optimization of Sex Chromosome Linked CHD Gene for Genetic Sexing of Domestic Chickens (Gallus domesticus)
December 1, 2017
Genetics
Abstract
Abstract Chromodomain Helicase DNA (CHD) binding protein loci is one of the sex chromosome linked gene found in most avian species including domestic chickens. CHD genes
Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts
October 1, 2017
Twin Research
Journal Article
Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences
Genetic and other risk factors for suicidal ideation and the relationship with depression
October 1, 2017
Suicide
Journal Article
There is a genetic contribution to the risk of suicide, but sparse prior research on the genetics of suicidal ideation.
Quality assurance of biospecimens for biobanking purposes: Sri Lankan Twin Registry Biobank
July 13, 2017
Genetics
Abstract
Quality assurance is a vital component in biobanking to assure integrity and viability of samples. Although standards are established for biobanking in the western world,
Developing a center for genetic research and capacity building of early-career scientists in Sri Lanka
July 13, 2017
Genetics
Abstract
Genetics plays an important role in health research. Shortage of infrastructure limits the genetics research output from within the country. Moreover poor practical and analytical
A systematic review of the Dementia Research in Sri Lanka
March 7, 2017
Systematic Reviews
Journal Article
The aim of this systematic review is to describe dementia research in Sri Lanka. This information will inform on dementia prevalence, person with dementia and caregiver
Integrating mental health into primary care for post‑conflict populations: A pilot study
February 21, 2016
Migration Research
Journal Article
Mental health care in post-conflict settings is often not prioritized, despite its important public health role. There is a salient gap in integrating mental health
Discrimination in the workplace, reported by people with major depressive disorder: a cross-sectional study in 35 countries
February 1, 2016
Common Mental Disorders
Journal Article
Whereas employment has been shown to be beneficial for people with Major Depressive Disorder (MDD) across different cultures, employers’ attitudes have been shown to be
Exposure to conflict and disaster: A national survey on the prevalence of psychotic experiences in Sri Lanka
January 1, 2016
Disaster Management
,
Tsunami
Journal Article
Recent research conducted in high-income countries suggests psychotic experiences are common in the general population, but evidence from low- and middle-income countries (LMIC) remains limited.
Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project
October 15, 2015
Twin Research
Journal Article
A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this
Promotion and Reporting of Research from Resource-Limited Settings
September 1, 2015
Capacity Building
Journal Article
Driven by global burden of disease and inequalities in health care, research activities in resource-poor settings have radically increased. However, a corresponding increase in reporting
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
August 1, 2015
Mental health of displaced and returnee populations: Insight from the Sri Lankan post-conflict experience
August 1, 2015
Migration Research
Journal Article
The month of May 2015 marked the sixth year since the end of conflict in Sri Lanka. The cause of death, destruction and displacement, three
The prevalence and correlates of alcohol use and alcohol use disorders: a population based study in Colombo, Sri Lanka
July 1, 2015